IARC Group 3 carcinogens


Methylene diphenyl 4,4'-diisocyanate, most often abbreviated as 4,4'-MDI and also known as Pure MDI, is the isocyanate used as the monomer feedstock for polyurethane production. It is a large commodity chemical compound ...more on Wikipedia about "4,4'-MDI"

4-Aminobenzoic acid, para-aminobenzoic acid, or simply PABA, is an organic compound with molecular formula C7H7NO2. PABA is a white crystalline substance that is only slightly soluble in water. It consists of a benzene ring substituted with an amino group and a carboxylic acid. ...more on Wikipedia about "4-Aminobenzoic acid"

Aldrin is a organochlorine insecticide which is oxidized in the insect to form dieldrin, a neurotoxin. Aldrin was formerly used to kill soil insects such as termites and grasshoppers to protect crops such as corn and potatoes. It has been classified as a persistent organic pollutant. Due to health concerns regarding dieldrin, it is no longer manufactured or used in the United States. In addition, aldrin is itself a carcinogen and mutagen. ...more on Wikipedia about "Aldrin"

Aniline, phenylamine or aminobenzene ( C6 H5 N H2) is an organic chemical compound which is a primary aromatic amine consisting of a benzene ring and an amino group. The chemical structure of aniline is shown at the right. ...more on Wikipedia about "Aniline"

1-Bromoethane, also known as ethyl bromide is a chemical compound of the haloalkanes group. It is used as an ethylating agent in organic synthesis. ...more on Wikipedia about "Bromoethane"

Cyclohexanone (also known as oxocyclohexane, pimelic ketone, ketohexamethylene, cyclohexyl ketone or ketocyclohexane) is a six-carbon cyclic molecule with a ketone functional group. It is a colorless, oily liquid with an acetone-like smell. Cyclohexanone is slightly soluble in water (5-10 g/100 ml), but miscible with the most common organic solvents. ...more on Wikipedia about "Cyclohexanone"

Diazomethane which is a toxic, explosive yellow gas, is one of the more common diazo compounds. It is usually prepared as a solution in ether and often used in laboratory procedures for converting carboxylic acids into their methyl esters or into their homologues. Diazomethane is prepared in the laboratory at mmol scale from diazomethane precursors such as Diazald or N-methyl-N-nitroso-p-toluenesulfonamide and MNNG or 1-methyl-3-nitro-1-nitrosoguanidine. Diazald in a solution of diglyme and diethyl ether reacts with a solution of potassium hydroxide in water at elevated temperatures and generated diazomethane is collected by distillation. Diazomethane is liberated from a solution of MNNG in diethyl ether by addition of sodium hydroxide in water at low temperatures. ...more on Wikipedia about "Diazomethane"

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Dioxin is the popular name for the family of chlorinated organic compounds comprising of Polychlorinated Dibenzo Furans (PCDF) and Polychlorinated Dibenzo Dioxins (PCDD). PCDD/F's have been shown to bioaccumulate in humans and wildlife due to their lipophilic properties. ...more on Wikipedia about "Dioxin"

Gold thioglucose is a neurotoxin. It is believed to bind to and destroy glucose receptors in the central nervous system. It has been used in animal tests on appetite and satiation. ...more on Wikipedia about "Gold thioglucose"

Hydroquinone, also benzene-1,4-diol, is an aromatic organic compound which is a type of phenol, having the chemical formula C6H4(OH)2. Its chemical structure, shown in the table at right, has two hydroxyl groups bonded to a benzene ring in a para position. It is a white granular solid at room temperature and pressure. ...more on Wikipedia about "Hydroquinone"

Iodomethane, commonly called methyl iodide, is a dense volatile liquid. It is clear and colourless, though it is light sensitive and may develop a purplish tinge caused by iodine, thus it is usually stabilised by storage over copper metal. Methyl iodide is widely used in organic synthesis to deliver a methyl group into a structure, a process called methylation, usually via SN2 substitution. It is naturally emitted by rice plantations in small amounts. ...more on Wikipedia about "Iodomethane"

Substances, mixtures and exposure circumstances in this list have been classified by the IARC as Group 3: The agent (mixture or exposure circumstance) is not classifiable as to its carcinogenicity to humans. This category is used most commonly for agents, mixtures and exposure circumstances for which the evidence of carcinogenicity is inadequate in humans and inadequate or limited in experimental animals. Exceptionally, agents (mixtures) for which the evidence of carcinogenicity is inadequate in humans but sufficient in experimental animals may be placed in this category when there is strong evidence that the mechanism of carcinogenicity in experimental animals does not operate in humans. Agents, mixtures and exposure circumstances that do not fall into any other group are also placed in this category. ...more on Wikipedia about "List of IARC Group 3 carcinogens"

Methyl Red, also called C.I. Acid Red 2, is an indicator dye that turns red in acidic solutions. Its formula is C15H15N3O2. It is an azo dye. It is a dark red crystalline powder with melting point between 179-182 °C. ...more on Wikipedia about "Methyl red"

Nessler's reagent is a reagent used to detect small amounts of ammonia. It is a 0.09 mol/L solution of potassium tetraiodomercurate(II) (K2[HgI4]) in 2.5 mol/L potassium hydroxide. A yellow coloration indicates the presence of ammonia: at higher concentrations, a brown precipitate may form. The sensitivity as a spot test is about 0.3 μg NH3 in 2 μL. ...more on Wikipedia about "Nessler's reagent"

Perylene or perilene is a polycyclic aromatic hydrocarbon with chemical formula 20 12 and CAS number 198-55-0, occurring as a brown solid. It or its derivatives may be carcinogenic, and it is considered to be a hazardous pollutant. In cell membrane cytochemistry, perylene is used as a fluorescent lipid probe. ...more on Wikipedia about "Perylene"

Phenol, also known under the old name carbolic acid, is a colorless crystalline solid with a typical sweet tarry odor. Its chemical formula is C6 H5 O H and its structure is that of a hydroxyl group (-OH) bonded to a phenyl ring; it is thus an aromatic compound. ...more on Wikipedia about "Phenol"

Resorcinol (or resorcin) is the 1,3- isomer of benzenediol. It is also known with a variety of other names, including: m-dihydroxybenzene, 1,3-benzenediol, 1,3-dihydroxybenzene, 3-hydroxyphenol, m-hydroquinone, m-benzenediol, and 3-hydroxycyclohexadien-1-one. ...more on Wikipedia about "Resorcinol"

Sulfur dioxide (also sulphur dioxide, sulfurous anhydride or sulphurous anhydride) has the chemical formula S O2. The gas is irritating to the lungs and is frequently described as smelling of burning sulfur. ...more on Wikipedia about "Sulfur dioxide"

Theobromine is a bitter alkaloid of the methylxanthine family, which also includes the similar compounds theophylline and caffeine. Despite its name, the compound contains no bromine — theobromine is derived from Theobroma, the genus of the cacao tree, which is composed of the Greek roots theo (" God") and broma ("food"), meaning "food of the gods". ...more on Wikipedia about "Theobromine"

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