Acquired immunodeficiency syndrome, or acquired immune deficiency syndrome (or acronym AIDS or Aids), is a collection of symptoms and infections resulting from the specific damage to the immune system caused by infection with the human immunodeficiency virus (HIV). AIDS is a condition that results from the latter stages of advanced HIV infection in humans, thereby leaving compromised indivduals prone to opportunistic infections and tumors. Although treatments for both AIDS and HIV exist to slow the virus' progression in a human patient, there is no known cure. ...more on Wikipedia about "AIDS"
Anti-nuclear antibodies are antibodies directed against the cell nucleus. They are raised in several conditions, usually in an auto-immune condition where the immune system makes antibodies to fight its own body. Normally a test (see External Links) is administered in people with many arthritic type symptoms or skin rashes. The rashes could be over both cheeks and shaped like a butterfly, or a wolf. They are known to effect almost any part of the body including kidneys and brain. The most popular auto-immune disease systemic lupus erythematosus(SLE). ...more on Wikipedia about "Antinuclear antibodies"
Asplenia refers to the absence ('a-') of normal spleen function and is associated with some risks. Asplenia may be congenital ( congenital asplenia), or acquired through surgery ( splenectomy) or through processes that destroy the spleen, generally through its function to filter the blood and therefore referred to as autosplenectomy (eg spherocytosis and sickle-cell disease). ...more on Wikipedia about "Asplenia"
An autosplenectomy occurs when a disease damages the spleen to such an extent that it is non-functioning and so equivalent to the spleen having been surgically removed ( splenectomy). This may occur in sickle-cell disease and spherocytosis. ...more on Wikipedia about "Autosplenectomy"
Chronic fatigue syndrome (CFS), also known as myalgic encephalomyelitis (ME), post-viral fatigue syndrome (PVFS) and various other names, is a syndrome of unknown and possibly multiple etiology, affecting the central nervous system (CNS), immune, and many other systems and organs. Most definitions other than the 1991 UK "Oxford", require a number of features, the most common being severe mental and physical depletion, which according to the 1994 Fukuda definition is "unrelieved by rest", and is usually made worse by even trivial exertion (controversially the Oxford and Fukuda require this to be optional only). However, patients usually contend that they have many, often severe symptoms which are far more onerous than the research diagnostic criteria, such as pain, muscle weakness, loss of brain function, hypersensitivity, orthostatic intolerance, digestive disturbances, depression, immune and in some cases life-threatening cardiac and respiratory problems, and it is these symptoms exacerbated by extremely low stamina that cause greatest suffering, not "fatigue", which more properly describes a normal state of recovery unrelated to pathology. Some cases resolve or improve over time, and where available, treatments bring a degree of improvement to many others. ...more on Wikipedia about "Chronic fatigue syndrome"
In medicine ( genetics and pediatrics) chronic granulomatous disease (CGD) is a hereditary disease where neutrophil granulocytes are unable to destroy ingested pathogens. It leads to the formation of granulomata in many organs. ...more on Wikipedia about "Chronic granulomatous disease"
Gulf War syndrome (GWS) is the name given to a variety of psychological and physical symptoms, including increases in the rate of immune system disorders and birth defects, reported by veterans of the Gulf War. It has not always been clear whether these symptoms were related to Gulf War service. Symptoms attributed to this syndrome have often been wide-ranging and sometimes poorly defined. They often include chronic fatigue, loss of muscle control, diarrhea, migraines, dizziness, memory problems and loss of balance. ...more on Wikipedia about "Gulf War syndrome"
Immune reconstitution inflammatory syndrome (IRIS) or immune reconstitution syndrome (IRS) is a rare condition seen in some cases of AIDS or immunosuppression, in which the immune system begins to recover, but then responds to a previously acquired opportunistic infection with an overwhelming inflammatory response that paradoxically makes the symptoms of infection worse. ...more on Wikipedia about "Immune reconstitution inflammatory syndrome"
In medicine, immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent. Most cases of immunodeficiency are either congenital or acquired. A person who has an immunodeficiency is said to be immunocompromised. An immunocompromised person is very vulnerable to opportunistic infections. ...more on Wikipedia about "Immunodeficiency"
Leukocyte adhesion deficiency, abbreviated LAD, is a rare autosomal recessive disorder characterized by immunodeficiency resulting in recurrent infections. The disorder is often divided into two separate genotypes called type I and type II, with type II being associated with fewer infections but more developmental delay. ...more on Wikipedia about "Leukocyte adhesion deficiency"
Mastocytosis is a group of rare disorders of both children and adults caused by the presence of too many mast cells (mastocytes) in a person's body. ...more on Wikipedia about "Mastocytosis"
Membranous nephropathy (or membranous nephritis, or membranous glomerulonephritis) is an immunologic renal disorder characterized by subepithelial immune deposits in the glomerular capillary wall. The subepithelial deposits are antigen- antibody complexes. They are formed by antibodies against cationic antigens crossing the anionic glomerular barrier or by circulating antigens. Although primary membranous predominantly has subepithelial deposits, secondary membranous may be characterized by subendothelial deposits and mesangial deposits. Rheumatoid arthritis itself can be associated with secondary MN. Drugs associated with rheumatoid arthritis such as penicillamine, gold salts, and some NSAIDs (such as Diclofenac) can also be associated with membranous nephritis. Other diseases associated with MN include lupus nephritis (WHO class V), Sjogren's disease, sarcoidosis, Hepatitis B virus, Hepatitis C virus. The only MN with a low complement level are lupus nephritis and Hepatitis B Virus (associated with elevated transaminases, Hepatitis B antigens). ...more on Wikipedia about "Membranous nephritis"
Myeloperoxidase deficiency is a genetic disorder featuring deficiency of myeloperoxidase. It presents with immune deficiency (especially candida albicans infections), although many people with MPO deficiency do not have a severe phenotype and do not have infections. ...more on Wikipedia about "Myeloperoxidase deficiency"
Pityriasis lichenoides chronica, short form PLC, is the chronic version of the Pityriasis lichenoides et varioliformis acuta, also called Mucha Habermann's Disease. ...more on Wikipedia about "Pityriasis lichenoides chronica"
Pityriasis Lichenoides et Varioliformis Acuta, or Mucha Habermann's Disease, short form PLEVA, is a disease of the immune system. It is the more severe version of Pityriasis lichenoides chronica. The disease is characterized by rashes and small lesions on the skin. It is not contagious and currently there is no cure for the disease, although the lesions can be treated with ultraviolet therapy as well as topical steroides and antibiotics. The disease is most common in males and usually accures in childhood, although it has been seen in every race and age group. It is possible for the disease to go into remission for short periods of time or forever. It is commonly misdiagnosed, the most common way to diagnose is by biopsy. This disease has not been known to be life threatening. There is no known cause of this disease, however many links from viruses, vaccines, and other illnesses have been made. The easiest way to understand this disease is to think of it like this. Everyone has T cells that fight disease, In a person with PLEVA the T cells get mixed up and decide to form in the skin causing the lesions. It is unknown why this happens. ...more on Wikipedia about "Pityriasis lichenoides et varioliformis acuta"
Severe Combined Immunodeficiency, or SCID, is a genetic disorder in which both "arms" ( B cells and T cells) of the adaptive immune system are crippled, due to a defect in one of several possible genes. SCID is a severe form of heritable immunodeficiency. It is also known as the "bubble boy" disease because its victims are extremely vulnerable to infectious diseases and must live (if untreated) in a completely sterile environment. The most famous case is the boy David Vetter. ...more on Wikipedia about "Severe combined immunodeficiency"
Transplant rejection occurs when the immune system of the recipient of an transplant attacks the transplanted organ or tissue. This is because a normal healthy human immune system can distinguish foreign tissues and attempts to destroy them, just as it attempts to destroy infective organisms such as bacteria and viruses. ...more on Wikipedia about "Transplant rejection"
Wiskott-Aldrich syndrome (WAS) is a rare X-linked recessive disease characterized by eczema, thrombocytopenia (low platelet counts), immune deficiency, and bloody diarrhea (due to the low platelet counts). It is also sometimes called the eczema-thrombocytopenia-immunodeficiency syndrome in keeping with Aldrich's original description in 1954. ...more on Wikipedia about "Wiskott-Aldrich syndrome"
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