Intracellular receptors Intracellular receptors The androgen receptor is an intracellular steroid receptor that specifically binds testosterone and dihydrotestosterone. ...more on Wikipedia about "Androgen receptor"
An estrogen receptor is a receptor for estrogens such as estradiol (the main endogenous human estrogen). Estrogen receptors are intracellular proteins like other steroid hormone receptors. Some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen . There are two distinct estrogen receptor genes, ESR1 and ESR2. Both estrogen receptor subtypes have a DNA-binding domain and can function as transcription factors to regulate the production of proteins. Both receptors also have functions independent of DNA binding . ...more on Wikipedia about "Estrogen receptor"
The glucocorticoid receptor (GR) is a ligand-activated intracytoplasmatic transcription factor that interacts with high affinity to cortisol and other glucocorticoids. ...more on Wikipedia about "Glucocorticoid receptor"
Intracellular receptors or nuclear receptors are a class of receptor located inside the cell rather than on its cell membrane. Their ligands (substances that bind to them) are hormones, eicosanoids, vitamins ( vitamin A and vitamin D) and various other substances. ...more on Wikipedia about "Intracellular receptor"
In cell biology, peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptor isoforms that exist across biology. Originally identified in Xenopus frogs as receptors that induce the proliferation of peroxisomes in cells, they are intimately connected to the cellular metabolism ( carbohydrate, lipid and protein) and cell differentiation. They are transcription factors. ...more on Wikipedia about "Peroxisome proliferator-activated receptor"
The progesterone receptor is an intracellular steroid receptor that specifically binds progesterone. Expressed by a single gene ( chromosome 11q22), it has two main forms, A and B, that differ in their molecular weight. ...more on Wikipedia about "Progesterone receptor"
Sex hormone receptors belong to the group of steroid hormone receptors and interact with sex hormones. Three sex hormone steroid receptors can be distinguished: ...more on Wikipedia about "Sex hormone receptor"
Steroid hormone receptors are intracellular (typically cytoplasmatic) receptors that perform signal transduction for steroid hormones. Steroid hormone receptors are part of the nuclear receptor family that include a group of homologous structured receptors (type II receptors) that bind to non-steroid ligands such as thyroid hormones and vitamin A, as well as to vitamin D, and orphan receptors. All these receptors are transcription factors thought to be derived from a common ancestor gene. ...more on Wikipedia about "Steroid hormone receptor"
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